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Evere cases may result in coma and even death. ou should seek immediate medical attention if you experience these symptoms while taking the medications.The major diclofenac metabolite, 4'hydroxy-diclofenac, has very weak pharmacologic activity. The formation of 4'-hydroxy diclofenac is primarily mediated by CPY2C9.

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Philadelphia: Lippincott Williams Wilkins.Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

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