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Trazodone
Clinical data
Trade namesMany brand names worldwide [1]
AHFS/Drugs.comMonograph
MedlinePlusa681038
Pregnancy categoryUS: C (Risk not ruled out)
Routes of administrationBy mouth (tablets)
ATC codeN06AX05 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilityBy mouth: 65% [3]
Protein binding89–95% [4]
MetabolismLiver (CYP3A4) [2]
MetabolitesmCPP [5]
Onset of actionBy mouth: 1 hour (T max ) [6]
Elimination half-lifeTrazodone IR: 7 hours [3] Trazodone ER: 10 hours [3] mCPP: 4–8 hours [7]
ExcretionUrine: 70–75% [3] Feces: 21% [3]

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3 After MAOIs, SNRIs and SSRIs are the most of serotonergic effects, as their main active is to find serotonin. The SNRI venlafaxine weapons toxicity more often than SSRIs do, timely because it has another serotonergic activity other than a reuptake inhibitor. Certain picked opioids what cold medicine can i take with duloxetine as tramadol, methadone, meperidine, fentanyl, and dextromethorphan are designed serotonin reuptake inhibitors and can cause death, but opioids with a day parenteral to morphine are not reuptake inhibitors, meaning that blood, codeine, oxycodone, and buprenorphine do not co ordination.

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With more generalized anxiety, trazodone will likely be prescribed for daily use in order to manage the issue. When the can i take flexeril with trazodone that triggers anxiety can be predicted, as in fireworks, thunderstorms, or the owner leaving the house, trazodone can also be used on an as-needed basis.The combination seems to put me to sleep and keep me asleep.

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Several antiepileptic drugs are used in the treatment of bipolar disorder, including valproic acid Depakene carbamazepine Tegretol and lamotrigine Lamictal However, data on the fetal effects of these drugs come primarily from studies of women with seizures.If it doesn t work, you should consider a sleep study with duloxetine 69 mg.

ntreated insomnia can cause weight gain, high blood pressure and other problems.

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Trazodone was approved for medical use in December 1981 in the US by the FDA as an anti-depressant medication, Desyrel. However, trazodone is a less effective anti-depressant than many other agents.edation and impairment of attention, judgment, thinking, and psychomotor skills may increase.

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Abilify, or aripiprazole, is an atypical neuroleptic aka anti-psychotic, or tranquilizer It can be used to treat delusions, hallucinations, and is also used in depression and bipolar disorder. have used it with some success to augment antidepressants in older adults with depression, but as a Geriatrician I don't treat those in a middle-aged age group in general.40263-012-0010-5.

ubMed: 3192413Mandrioli R, Protti M, Mercolini L: New-Generation, Non-SSRI Antidepressants: Therapeutic Drug Monitoring and Pharmacological Interactions.

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