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If PRES is suspected or diagnosed, blood pressure tacrolimus chemical structure should be maintained and immediate reduction of immunosuppression is advised.In a U. tacrolimus chemical structure, the ratio of whole blood concentration to plasma concentration averaged 35 range 12 to 67 Tacrolimus is extensively metabolized by the mixed-function oxidase system, primarily the cytochrome P-450 system CYP3A A metabolic pathway leading to the formation of 8 possible metabolites has been proposed.
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