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Some products that may interact with this drug are: tetracyclines (such as minocycline, tetracycline) vitamin A-type drugs (such as acitretin, bexarotene) vitamin A, drugs that cause bone loss (for example, anti-seizure drugs such as phenytoin, corticosteroids such as prednisone) Tell your doctor when you start any new drug, and discuss if you should use additional reliable birth control. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. Sotret (isotretinoin) pkg. 5 mg 10 amount of packaging.

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Isotretinoin
Clinical data
PronunciationSee note at tretinoin
Trade namesAccutane (originator), others [1]
AHFS/Drugs.comMonograph
MedlinePlusa681043
License dataUS   FDA: Isotretinoin
Pregnancy categoryAU: X (High risk) US: X (Contraindicated)
Routes of administrationBy mouth, topical
ATC codeD10AD04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityVariable
Protein binding99.9%
MetabolismHepatic
Elimination half-life10–20 hours
ExcretionRenal and fecal

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  2. Active substance: isotretinoin
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