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Your doctor may need to adjust your diabetes medicatio (s) Tell your doctor right away of any serious side effects, including: signs of kidney problems (such as change in the amount of urine) joint pain, unusual skin blisters, signs of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain) Get medical help right away if you have any very serious side effects, including: signs of pancreatitis (such as persistent nausea/vomiting, loss of appetite, severe stomach/abdominal/back pain) A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat) severe dizziness, trouble breathing. Januvia (sitagliptin) packing 100 mg 10 the amount of packaging.

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If pancreatitis is suspected, promptly discontinue JANUVIA and sitagliptin dose with metformin appropriate management.Medical history of active liver disease other than non-alcoholic hepatic steatosis including chronic active hepatitis B or C, primary biliary cirrhosis, or symptomatic gallbladder disease. Chronic myopathy, mitochondrial disorder, or a progressive neurological or neuromuscular disorder e.

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It also decreases glucose production and absorption from the liver. However, sitagliptin metformin patients cannot reach their A1C goal with metformin alone and need to add on extra medication.In clinical studies, as described below, sitagliptin did not meaningfully alter the pharmacokinetics of metformin, glyburide, sitagliptin metformin, rosiglitazone, warfarin, or oral sitagliptin metformin, providing in vivo evidence of a low propensity for causing drug interactions with substrates of CYP3A4, CYP2C8, CYP2C9, and organic cationic transporter OCT Metformin: Co-administration of sitagliptin metformin twice-daily doses of sitagliptin with metformin, an OCT substrate, did not meaningfully alter the pharmacokinetics of metformin in patients with type 2 diabetes.

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She asked about what last medication I had been taking.Type 2 diabetes is a serious medical condition and should be metformin sitagliptin under the regular care of a physician.

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In patients given JANUVIA in combination with metformin. In the study of JANUVIA as initial therapy with pioglitazone, one patient taking JANUVIA experienced a severe episode of hypoglycemia.9 episodes/patient-year for JANUVIA 100 mg in combination with glimepiride with or without metformin.

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Ot for people with severe kidney problems.Caution should be used to ensure that the correct dosage of sitagliptin is prescribed for patients with moderate or metformin sitagliptin renal impairment.

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And, if pancreatitis becomes chronic, the inflammation of the pancreas will alter its normal structure and functions. Our metformin sitagliptin drug lawyers believe that Merck fail Januvia is an orally-active inhibitor of the dipeptidylpeptidase-4 DPP-4 enzyme.Any unauthorized or illegal use, copying or dissemination will be prosecuted.

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