Talk to your doctor if you are using marijuana (cannabis) Quetiapine may cause a condition that affects the heart rhythm (QT prolongation) QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. Seroquel (quetiapine) pkge. 100 mg 120 package quantity.
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Cochrane Database Syst Rev. 2019 Dec. D010557. doi. D010557.
|Pronunciation||/ k w ɪ ˈ t aɪ . ə p iː n / kwi- TY -ə-peen|
|Trade names||Seroquel, Temprolide, others|
|License data||US FDA: Quetiapine|
|Pregnancy category||AU: B3 US: C (Risk not ruled out)|
|Routes of administration||By mouth|
|ATC code||N05AH04 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Protein binding||83% |
|Metabolism||Liver via CYP3A4-catalysed sulfoxidation to its active metabolite norquetiapine (N-desalkylquetiapine) |
|Elimination half-life||7 hours (parent compound); 9–12 hours (active metabolite, norquetiapine)  |
|Excretion||Kidney (73%), faeces (20%)    |
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