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Metoclopramide
Clinical data
Pronunciation/ ˌ m ɛ t ə ˈ k l ɒ p r ə m aɪ d /
Trade namesPrimperan, Reglan, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa684035
License dataUS   FDA: Metoclopramide
Pregnancy categoryAU: A US: B (No risk in non-human studies)
Routes of administrationBy mouth, intravenous, intramuscular
Drug classD 2 receptor antagonist; 5-HT 3 receptor antagonist; 5-HT 4 receptor agonist; Prolactin releaser
ATC codeA03FA01 ( WHO )
Legal status
Legal statusAU: S3 (combination with paracetamol), S4 (alone) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability80 ± 15% (by mouth)
MetabolismLiver
Elimination half-life5–6 hours
ExcretionUrine: 70–85% Feces: 2%

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5. Which of the following would you do? A. Stop the metoclopramide (eg. Reglan ). B. Stop the prochlorperazine. (Compazine). C. Stop the valproate (Depakote).

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    What is the drug classification for reglan?

    .

    When a reglan for diarrhea has low prolactin levels, milk supply may be affected. Prolactin levels are primarily regulated by inhibition: the presence of prolactin-inhibiting factors dopamine is the principal one keep prolactin levels in check.Convulsive seizures have been reported, especially in patients with epilepsy; however, there is no obvious association with use of this drug.

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