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Ranitidine
Clinical data
Pronunciation/ r ə ˈ n ɪ t ɪ d iː n /
Trade namesZantac, others
AHFS/Drugs.comMonograph
MedlinePlusa601106
License dataUS   FDA: Ranitidine
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth, IV
ATC codeA02BA02 ( WHO ) A02BA07 ( WHO ) (ranitidine bismuth citrate)
Legal status
Legal statusAU: S2 (Pharmacy only) UK: General sales list (GSL, OTC) US: OTC / Rx-only
Pharmacokinetic data
Bioavailability50% (by mouth) [1]
Protein binding15%
MetabolismHepatic: FMOs, including FMO3; other enzymes
Onset of action55–65 minutes (150 mg dose) [2] 55–115 minutes (75 mg dose) [2]
Elimination half-life2–3 hours
Excretion30–70% Renal

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