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Cyproheptadine
Clinical data
Pronunciation( / ˌ s aɪ p r oʊ ˈ h ɛ p t ə d iː n / [1]
Trade namesPeriactin, others
AHFS/Drugs.comMonograph
MedlinePlusa682541
License dataUS  DailyMed:  54686520-506f-7765-7220-436f736d6963
Pregnancy categoryAU: A US: B (No risk in non-human studies)
Routes of administrationOral
ATC codeR06AX02 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) CA : OTC UK: General sales list (GSL, OTC) US: ℞-only
Pharmacokinetic data
Protein binding96 to 99%
MetabolismHepatic. [2] [3] Mostly CYP3A4 mediated.
Elimination half-life8.6 hours [4]
ExcretionFaecal (2-20%; 34% of this as unchanged drug) and renal (40%; none as unchanged drug) [2] [3]

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