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Valaciclovir
Clinical data
Trade namesValtrex, Zelitrex, others
AHFS/Drugs.comMonograph
MedlinePlusa695010
License dataUS   FDA: Valacyclovir
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationBy mouth
ATC codeJ05AB11 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability55%
Protein binding13–18%
MetabolismLiver (to aciclovir)
Elimination half-life<30 minutes (valaciclovir); 2.5–3.6 hours (aciclovir)
ExcretionKidney 40–50% (aciclovir), faecal 47% (aciclovir)

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