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|Trade names||Provigil, Alertec, Modavigil, others|
|License data||US FDA: Modafinil|
|Pregnancy category||AU: B3 US: C (Risk not ruled out) |
|Dependence liability||Psychological: Very low  Physical: Negligible |
|Addiction liability||Very low to low |
|Routes of administration||By mouth (tablets) |
|ATC code||N06BA07 ( WHO )|
|Legal status||AU: S4 (Prescription only) UK: POM (Prescription only) US: Schedule IV|
|Bioavailability||Not determined due to the aqueous insolubility|
|Metabolism||Hepatic (primarily via amide hydrolysis;  CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5 involved |
|Elimination half-life||15 hours ( R -enantiomer), 4 hours ( S -enantiomer) |
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Stacey M Cobb, MD Fellow in Developmental and Behavioral Pediatrics, Clinical Instructor, Department of Pediatrics, Medical University of South Carolina College of Medicine Stacey M Cobb, MD is a member of the following medical societies: Alpha Omega Alpha, Why is generic provigil so expensive Academy of Pediatrics, Society for Developmental and Behavioral PediatricsDisclosure: Nothing to disclose.
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