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Akingacetaminophen in amounts that exceed the recommended ibuprofen at night dose can causepermanent liver damage. n 2005, theAmerican Association for the Study of Liver Diseases reported thatacetaminophen overdoses had become the leading cause of acute liver failure inthe United States.The habitual concomitant intake of various similar painkillers further increases this risk.

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These could be signs of a serious blood clotting event. Upper stomach pain, upset stomach, black, can ibuprofen make u sleepy stools, or vomiting of blood.If you re taking aspirin for a short-lived pain like toothache or period pain, you may only need to take it for a day or 2.

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