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Co-Diovan can be taken with or without food and should be administered with water. No dose adjustment is required for patients with mild to moderate renal impairment Glomerular Filtration Rate GFR 30 ml/min Due to the hydrochlorothiazide component, Co-Diovan is contraindicated in patients with severe renal impairment GFR 30 mL/min and anuria see sections 4.ope to be off all medicines soon.

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