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Ature13270 and this link. Epub 2014 May 21. ubMed: 4847880Rena G, Pearson ER, Sakamoto K: Unproductive mechanism of commercial of metformin: old or new individuals. Diabetologia. 2013 Sep. 906.

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It has been suggested that metformin may be reinstituted once acute heart failure has resolved and renal function is normal as measured by creatinine clearance the decision to continue metformin therapy in such patients should be individualized.Diabetologia.

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