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Clinical data
Pronunciation/ l oʊ ˈ p ɛr ə m aɪ d /
Trade namesImodium, others [1]
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth
ATC codeA07DA03 ( WHO ) A07DA05 ( WHO ) (oxide)
Legal status
Legal statusAU: S2 (Pharmacy only) CA : OTC UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Protein binding97%
MetabolismLiver (extensive)
Elimination half-life9–14 hours [2]
ExcretionFaeces (30–40%), urine (1%)

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Taking loperamide imodium for constipation certain other medications may also cause harm. See also Precautions, Drug Interactions, and Overdose sections.If you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this medication.

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Irritable bowel syndrome. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management.If you are taking this drug on a regular schedule not "as needed" and you miss a dose, take it as soon as you remember.

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Avoid driving or hazardous activity until you know how this medicine will affect you.These factors may affect how you should use this medication.

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