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Loperamide
Clinical data
Pronunciation/ l oʊ ˈ p ɛr ə m aɪ d /
Trade namesImodium, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa682280
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth
ATC codeA07DA03 ( WHO ) A07DA05 ( WHO ) (oxide)
Legal status
Legal statusAU: S2 (Pharmacy only) CA : OTC UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability0.3%
Protein binding97%
MetabolismLiver (extensive)
Elimination half-life9–14 hours [2]
ExcretionFaeces (30–40%), urine (1%)

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