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Dose titration with the individual components is recommended. In each case, up-titration of individual components to the next dose should be followed in order to reduce the risk of hypotension and other adverse events.he information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.

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After oral administration of therapeutic doses of captopril, rapid absorption occurs with peak blood levels at about one hour.In these cases, your doctor may want to change the dose, or other precautions may be necessary.

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