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Metronidazole
Clinical data
Pronunciation/ m ɛ t r ə ˈ n aɪ d ə z oʊ l /
Trade namesFlagyl, Metro, others
AHFS/Drugs.comMonograph
License dataUS   FDA: Metronidazole
Pregnancy categoryAU: B2 US: B (No risk in non-human studies)
Routes of administrationby mouth, topical, rectal, IV, vaginal
ATC codeA01AB17 ( WHO ) D06BX01 ( WHO ), G01AF01 ( WHO ), J01XD01 ( WHO ), P01AB01 ( WHO ), QP51AA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability80% (by mouth), 60–80% (rectal), 20–25% (vaginal) [1] [2]
Protein binding20% [1] [2]
MetabolismHepatic [1] [2]
Elimination half-life8 hours [1] [2]
ExcretionUrine (77%), faeces (14%) [1] [2]

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Full Text. Tariq R, Singh S, Gupta A, Pardi DS, Khanna S. Association of gastric acid suppression with recurrent Clostridium difficile infection: a systematic review and meta-analysis. The information about each medicine appears in a box like this: 2007 Aug.

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