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Studies can finasteride cause depression the 5 alpha-reductase inhibitor finasteride demonstrate the dependency of prostate and male external genital differentiation on dihydrotestosterone DHT However, can finasteride cause depression androgen receptor blockade with flutamide, finasteride did not totally abolish prostate differentiation or completely feminize the external genitalia, despite increasingly higher doses.After 7 days of treatment plasma testosterone levels and DHT levels were assessed.

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