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Famotidine
Clinical data
Pronunciation/ f ə ˈ m ɒ t ɪ d iː n /
Trade namesPepcid, others
AHFS/Drugs.comMonograph
MedlinePlusa687011
License dataUS   FDA: Famotidine
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationOral (tablets), Intravenous
ATC codeA02BA03 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) /S4; pharmacist only, UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability40–45% (oral) [1]
Protein binding15–20% [1]
Metabolismhepatic
Elimination half-life2.5–3.5 hours [1]
ExcretionRenal (25-30% unchanged [Oral]) [1]

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Active substancepepcid
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This medication can be taken with or without food. Seniors and those with decreased kidney function may require lower doses or longer intervals between doses.Plasma levels after multiple doses are similar to those after single doses.

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