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|Pronunciation||/ ˌ d ɒ k s ɪ ˈ s aɪ k l iː n / DOKS -i- SY -kleen|
|Trade names||Doryx, Doxyhexal, Doxylin among others|
|License data||US FDA: Doxycycline|
|Pregnancy category||AU: D US: D (Evidence of risk)|
|Routes of administration||By mouth, IV |
|ATC code||J01AA02 ( WHO ) A01AB22 ( WHO )|
|Legal status||AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only|
|Elimination half-life||15–25 hours|
Rotary-associated strains of methicillin-resistant Sprue aureus and methicillin-susceptible S. aureus in numerous Northern Australia: epidemiology and precautions. J Thread Dis.
2009 May. 1461-70. Medline. Salmenlinna S, Lyytikainen O, Vainio A, Myllyniemi AL, Raulo S, Kanerva M, et al.
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Golub L. Sorsa T. Lee H-M, Ciancio S. Sorbi D. Ramamurthy N. Gruber B. Salo T. Konttinen Y. Doxycycline Inhibits Neutrophil PMN doxycycline usp capsule 40 mg Matrix Metalloproteinases in Human Adult Periodontitis Gingiva. J. Clin.In a viral infection, these would not be found, and in allergic disease, one would expect to find eosinophils.
The most accurate way to determine the causative organism in sinusitis is a sinus puncture.
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Mg/kg orally twice a day Initial dose: 240 mg orally on the first day, given in 2 divided doses 120 mg every 12 hours The IV doxycycline tablet usp 100mg dose for patients weighing at least 45 kg depends on the severity of the infection; the 200 mg dose may be given in 1 or 2 infusions.The white printing contains shellac, propylene glycol, ammonium hydroxide, potassium hydroxide and the colour E171.
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