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Therapy should be initiated at 25 mg/day.
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Activation of Mania or Hypomania: Prior to initiating treatment with ZOLOFT, patients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder.4 The literature suggests an association with serotonergic antidepressants inducing jaw pain/jaw spasm reversible syndrome.
Data from the pooled case reports above suggest that antidepressant-associated bruxism may occur in patients of any age, including children.
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Don't do it.QTc prolongation/Torsade de Pointes has been reported following sertraline overdose; therefore, ECG-monitoring is recommended in all ingestions of sertraline overdoses.
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Re breastfeeding or plan to breastfeed. A small amount of ZOLOFT may information on the drug zoloft into your breast milk.Adults and Pediatrics: Additional data: There are clinical trial and post-marketing reports with SSRIs and other newer antidepressants, in both pediatrics and adults, of severe agitation-type adverse events coupled with self-harm or harm to others.
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