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Mg 500 micrograms baclofen, 3. mg sodium.The pharmacokinetics of ITB therapy have been derived in 4 studies. Based on these studies1, Because baclofen is hydrophobic, it has difficulty passing the lipophilic membranes of cells in the spinal baclofen 10 mg tab and the baclofen 10 mg tab of it will remain in the CSF The intrathecal half-life of ITB therapy ranges from 1 to 5 hours similar to plasma baclofen3-4 hours CSF clearance is thought to take place by the turnover of CSF suggesting elimination is by bulk flow of CSF maximum activity is observed in 24 to 48 hours.
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